【摘要】 以微晶纤维素(MCC)为原料,经环氧化和醚化反应,制备了纤维素衍生物——纤维素苦味酸醚(MCC-PA)。通过红外光谱、元素分析对其进行结构表征,以氮质量分数为优化指标,考查了物料比、氢氧化钠(质量分数36%)的用量、反应温度和反应时间对纤维素苦味酸醚制备的影响。通过单因素试验得出合成条件为:m(苦味酸(PA)):m(环氧化纤维素)=5:1,NaOH用量为30mL,反应温度为45℃,反应时间为3h,此时产物的氮质量分数为2.22%。在模拟人体生理介质的条件下,测定了纤维素苦味酸醚对肌酐的吸附性能,绘制了吸附动力学曲线。结果表明,纤维素苦味酸醚对肌酐的吸附平衡时间为18h,对肌酐的最大吸附容量为2.49mg/g。更多还原

【Abstract】 Ether of microcrystalline cellulose-based picric acid(MCC-PA) was prepared from microcrystalline cellulose by the reactions of epoxidation and etherification.The structure of MCC-PA was analyzed by FTIR and element analyzer.Influences of reaction conditions,such as ratio of epoxy cellulose to picric acid(PA),volume of NaOH(36%,by weight),reaction time and reaction temperature,were studied.Results showed that the synthetical conditions were obtained as ratio of epoxy cellulose to picric acid 5:1(by weight),the volume of NaOH(36%) 30mL,reaction temperature 45 degrees C and reaction time 3 hours,and the nitrogen content of MCC-PA was 2.22% under this conditions.The adsorption property of MCC-PA to creatinine was studied under simulated biological conditions.The kinetic curve was given.Results showed that adsorption capacity reached an equilibrium value after 18 hours,and the maximum adsorption capacity was 2.49mg/g.更多还原