【摘要】 蛹虫草为珍稀中药材,基于为培养出含有类似天然冬虫夏草主要活性物质的蛹虫草提供基础依据的目的,对人工培养蛹虫草及菌丝体、子实体和冬虫夏草及菌丝体中的氨基酸、多糖、虫草素等活性物质含量与组成进行了测定,结果表明:人工培养蛹虫草与冬虫夏草在氨基酸种类上完全一致,但人工培养蛹虫草中赖氨酸、酪氨酸含量显著升高,组氨酸则显著降低;二者组成的多糖基本一致,但冬虫夏草特有一个分子质量约100 kD的组分,该组分占多糖总量的1.38%,人工培养的蛹虫草的虫草素含量显著高于冬虫夏草。以上成分的细微变化是否是造成二者药理活性差异的原因还有待研究。更多还原

【Abstract】 Cordyceps militaris is a rare traditional Chinese medicinal material.In order to provide basic information for culturing Cordyceps militaris to have similar active components with Cordyceps sinensis,the contents and compositions of amino acids,polysaccharides and cordycepin etc in cultured C.militaris and its mycelia and sporophores and in C.sinensis and its mycelia were determined.The results showed that the amino acid compositions were identical in both C.militaris and C.sinensis.However,the contents of Lys and Tyr in C.militaris were evidently higher than in C.sinensis,and the His content was reduced remarkably.Both C.militaris and C.sinensis had similar polysaccharide compositions.However,a specific ingredient of polysaccharides was detected in C.sinensis.Its molecular weight was about 100 kD,and accounted for 1.38% of the total polysaccarides.The content of cordycepin in C.militaris was remarkably higher than that in C.sinensis.Whether the difference of these active components are responsible for their pharmacological activities remains for further studies.更多还原