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蒙成药嘎日迪-5对小鼠给药剂量与镇痛作用的相关性研究

Pertinence Studies of Administration Dosage and Paregoric Action of Mongolian Patent Medicine Ga-Ri-Di-5 to Mouse

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【作者】 王欢王秀兰吴龙堂乌日图

【Author】 WANG Huan WANG Xiu-lan WU Long-tang et al(1.Mongolian Pharmacy Pharmacology Staff Room of Mongolian Medcine and Pharmacy College of Inner Mongolia University for the Nationalities,Tong-liao 028000)

【机构】 内蒙古民族大学蒙医药学院国家民委-教育部重点实验室蒙药药理毒理实验室

【摘要】 目的:研究蒙成药嘎日迪-5对小鼠给药剂量与镇痛作用的相关性。方法:设蒙成药嘎日迪-5不同浓度给药组,比较各组间用热板法刺激小鼠足部产生疼痛反应时的痛阈值。结果:通过镇痛实验得出蒙成药嘎日迪-5不同浓度给药时对小鼠痛阈值有相应的显著差异。结论:初步研究证明蒙成药嘎日迪-5对小鼠给药剂量与镇痛作用之间有明显的量效关系。

【Abstract】 Objective: To study the pertinence of administration dosage and paregoric action of mongolian patent medicine Ga-Ri-Di-5 to mouse.Methods:Supposing the different concentrations of mongolian patent medicine Ga-Ri-Di-5,comparing the pain threshold when using hot-plate test to irritate the foot of mouse and produce the ache reaction.Results:From the paregoric experiment we can know that there is corresponding marked disparity of mouse pain threshold at different concentration administration of mongolian patent medicine Ga-Ri-Di-5.Conclusion:Preliminary studies certificate that there is marked dosis effect relation between administration dosage and paregoric action of mongolian patent medicine Ga-Ri-Di-5 to mouse.

  • 【文献出处】 成都中医药大学学报 ,Journal of Chengdu University of Traditional Chinese Medicine , 编辑部邮箱 ,2009年03期
  • 【分类号】R29
  • 【被引频次】6
  • 【下载频次】218
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