【摘要】 目的:探讨何首乌饮对衰老大鼠肾脏的保护作用。方法:D-半乳糖腹腔注射建立大鼠衰老模型,何首乌饮连续灌胃,肾组织切片HE染色,显微镜下观察肾组织形态学的变化并进行定量分析。结果:何首乌饮组的肾小球数目明显高于模型组(P<O.01),与正常组接近;肾小囊囊腔宽和肾小球直径明显低于模型组(P<0.01)。结论:何首乌饮能改善衰老大鼠肾脏的形态学结构,具有延缓肾脏老化的作用。更多还原

【Abstract】 Objective:To investigate the protective effects of HESHOUWU decoction on senile rats’ kidney. Methods:The senile model rats were made by abdominal injecting D-galactose;after the model was successfully established,the rats were adminstrated with HESHOUWU decoction.The slices of kidney were made by histological method and stained by HE staining.The morphological changes of kidney were observed under microscope and quantitatively analyzed.Results:The kidney glomerulus number of rats in HESHOUWU decoction group was obviously higher than in model group and approach normal rats(P<0.01);the renal capsule breadth and the kidney glomerulus diameter were obviously lower than model group(P<0.01).Conclusions: HESHOUWU decoction can improve the morphology of senile rats kidney and can delay renal senility of rats.更多还原