【摘要】 目的探讨尿微量白蛋白、血清胱抑素C水平对高血压、糖尿病早期肾功能损害的临床诊断价值评价。方法将研究对象分为高血压组、糖尿病组、阳性对照组及阴性对照组。取晨尿,免疫透射比浊法检测尿微量白蛋白;乳胶增强散射免疫比浊法检测血清胱抑素C;酶法检测血清肌酐和尿素氮。结果高血压组及糖尿病组患者尿微量白蛋白,血清胱抑素C水平均显示高于正常对照组(P<0.01),尿微量白蛋白和血清胱抑素C检出率显著高于阴性对照组。结论尿微量白蛋白和血清胱抑素C水平是肾功能损害的早期标志物;联合检测可提高糖尿病和高血压早期肾功能损害检出率。更多还原

【Abstract】 Objective To investigate the clinical value of UMA and SCys-C levels in the patients with early renal function injury caused by hypertension and diabetes mellitus.Methods All the cases were individed in to four groups:DM group;Hp group ;degenerative nephrosis group and healthy control group.UMA was detected with the immune transmission nephelometry.SCys-C was detected with grains strengthen immunoturbidimetry.Cr and BUN levels in serum were detected with enzymic method.Results UMA and SCys-C levels in hypertension and diabeticpatient were significantly higher than normal control(P<0.01).The abnormal rates for UMA and SCys-C were significantly higher those that of SCr and BUN.Conclusion The detections of UMA and SCys-C showed that they are sensitive indexes of early renal function injury.The conbined determination of UMA and SCys-C is useful for early diagnosis and intervention for hypertension and diabeticnephropathy.更多还原