【摘要】 目的:观察理肠汤合盐酸舍曲林片治疗腹泻型肠易激综合征的临床疗效。方法:将72例腹泻型肠易激综合征病人随机分为两组,治疗组37例,以自拟理肠汤(痛泻要方合金铃子散加味)同时口服盐酸舍曲林片50mg,每日晨起1次;对照组35例,单纯口服理肠汤。两组服药期间均停服其他药物,所有病例均给予心理疏导和饮食调整,疗程4周。结果:总有效率治疗组为86.5%,对照组为65.7%,两组比较,差异有显著性意义(P<0.05);两组治疗后主要症状积分均有明显改善,与治疗前比较,差异有显著性或非常显著性意义(P<0.05或P<0.01);除腹胀、排便不尽感外,治疗组与对照组治疗后比较,差异有显著性或非常显著性意义(P<0.05或P<0.01)。结论:理肠汤合盐酸舍曲林针对病因治以疏肝健脾、解郁安神,使患者身心逐渐进入一种良性循环状态,从而使病情得到明显改善。更多还原

【Abstract】 Objective:To observe the clinical curative e ect of treating diarrhea-predominant irritable bowel syndrome(D-IBS) with Lichang Tang(Intestine-Regulating Decoction) and sertraline hydrochloride.Methods:72 patients with(D-IBS) was randomly divided into 2 groups:32 cases in the treatment group was given self-prescribed Lichang Tang(modi ed Tongxie Yaofang [Main recipe for painful diarrhea]+Jinlingzi San [Toosendan Powder]) and sertraline hydrochloride(50 mg,p.o.once in the early morning);35 cases in the control group were given Lichang Tang alone for oral administration.During administering these drugs,other drugs were discontinued in the 2 groups.Psychological counseling and dietary modi cation were used in all patients.The course of treatment lasted for 4 weeks.Results:The total e ective rates in the treatment group and the control group were 86.49% and 65.71% respectively,and there was signi cant di erence(P<0.05);after treatment the main symptoms in both groups were markedly improved,there were signi cant and very signi cant di erences compared with those before treatment(P<0.05,P<0.01));comparing the symptoms(excluding abdominal distention and defecation incompletion feeling) before and after treatment in the treatment group and the control group,there were signi cant and very signi cant di erences(P<0.05,P<0.01).Conclusions:Conclusions:This etotropic method aims at soothing the liver,strengthening the spleen,resoling depression and tranquilizing the mind.The psychosomatic status of patients gradually gets into a benign circulation,consequently their states of illness are markedly improved.更多还原