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中药田基黄抗幽门螺杆菌的实验研究
Experimental study on resistance of hypericum japonicum Thunb.to helicobacter pylori
【摘要】 目的:观察田基黄对幽门螺杆菌(Hp)体外抑菌作用。方法:采用液体稀释法,将田基黄浸膏及提取物与幽门螺杆菌共同培养,通过比较细菌生长情况而测定田基黄浸膏及提取物的MIC和MBC。结果:田基黄浸膏及提取物对幽门螺杆菌均有明显抑杀作用。结论:浓度为25mg/ml田基黄浸膏和6.25mg生药/ml的提取物均可有效抑制幽门螺杆菌的生长。
【Abstract】 Objective:To observe the resistance of hypericum japonicum Thunb.to helicobacter pylori.Methods:Liquid dilution method was used to culture mixture of hypericum japonicum Thunb.extractum and helicobacter pylori,hypericum japonicum Thunb.extraction and helicobacter pylori respectively.The minimum inhibitory concentration and minimal bactericidal concentration of hypericum japonicum Thunb.extractum and extraction were determined by comparing the growth condition of helicobacter pylori.Results:Both of hypericum japonicum Thunb.extractum and extraction had obvious resistant effect on helicobacter pylori.Conclusion:25 mg/ml hypericum japonicum Thunb.extractum and 6.25 mg crude drug/ml hypericum japonicum Thunb.extraction can suppress the growth of helicobacter pylori effectively.
【Key words】 Helicobacter pylori; Hypericum japonicum Thunb.; Drug sensitivity; Experimental study;
- 【文献出处】 中华中医药杂志 ,China Journal of Traditional Chinese Medicine and Pharmacy , 编辑部邮箱 ,2009年06期
- 【分类号】R285.5
- 【被引频次】40
- 【下载频次】498