【摘要】 目的:分析脑梗死的弥散张量成像(DTI)和弥散加权成像(DWI)的影像表现,评价其临床应用价值。方法:对84例不同时期(超急性期6例,急性期30例,亚急性期26例,慢性期22例)脑梗死患者行常规磁共振成像(MRI)、DWI及DTI扫描,比较患侧和健侧弥散信号的改变及表观弥散系数(ADC)、各项异性指数(FA)值的变化,分析不同时期脑梗死DWI信号改变、ADC值及FA值的关系。结果:超急性期、急性期和亚急性期病灶在DWI呈高信号,慢性期表现为低信号;亚急性期和慢性期平均相对表观弥散系数(rADC)值明显高于超急性期和急性期脑梗死病灶的平均rADC值(P<0.05)。45例不同时期(超急性期4例,急性期16例,亚急性期14例,慢性期11例)患者脑梗死区平均FA值明显低于健侧对应区的平均FA值(P<0.05)。结论:DWI和DTI可以快速检出超急性和急性期脑梗死,DWI和MRI的联合应用可以对脑梗死进行分期。更多还原

【Abstract】 Objective To analyze and evaluate the applications of diffusion tensor imaging(DTI) and diffusion weighted imaging(DWI) in cerebral infarction.Methods 84 cases with different phases cerebral infarction(6 cases in super-acute,30 cases in acute,26 cases in sub-acute and 22 cases in chronic phase) were performed by routine MRI,DWI and DTI scan,apparent diffusion coefficient(ADC),fractional anisotropy(FA) and the signal changes of DWI of the leision and the conlateral side were calculated and compared;The relationships among DWI,FA and ADC in different phases of cerebral infarction were analyzed.Results The leisons of super-acute and acute cerebral infarction showed obviously high signal on DWI images,and low signal in chronic cerebral infarction.The mean relative ADC (rADC) values of sub-acute and chronic cerebral infarction were higher than those of super-acute and acute cerebral infarction(P<0.05).The FA values in 45 cases with different phases cerebral infarction(4 cases in super-acute,16 cases in acute,14 cases in sub-acute and 11 cases in chronic phase) were all lower than those in conlateral regions(P<0.05).Conclusion DWI and DTI can detect superacute and acute lesions,the combination of DWI and conventional MRI can differentiate the phases of cerebral infarction.更多还原