【摘要】 背景与目的:肥胖被证实为增加结直肠癌的重要因素。有研究表明,无论对于男性还是女性,体质指数(body mass index,BMI)都与结肠癌的发病率有密切关系。因此,本研究探讨BMI与我国结肠癌发病的关系,为结肠癌的预防提供参考。方法:用病例-对照研究方法分析707例首次确诊的结肠癌患者和709名健康人的BMI情况,比较两组人群BMI的情况。结果:首次确诊的结肠癌患者平均BMI为(24.52±4.56)kg/m2,健康对照人群平均BMI为(23.75±3.14)kg/m2,结肠癌患者的BMI明显高于健康对照人群(t=-3.72,P<0.001)。根据性别和年龄的不同进行分组后,可以看出结肠癌患者的BMI比健康对照组高。logistic回归分析,BMI的升高是结肠癌发生的危险因素,OR值为1.059(95%CI,1.029～1.090)。结论:汉族人结肠癌的发生与BMI有关。更多还原

【Abstract】 Background and Objective:Obesity is associated with increased risk of colorectal cancer.Many studies showed that body mass index(BMI) is related to the incidence of colon cancer.This study was to explore the relationship between BMI and colon cancer in Chinese population and provide evidences for the prevention of colon cancer.Methods:Clinical data, including BMI, of 707 colon cancer patients and 709 healthy subjects were compared.Results:The mean BMI was significantly higher in colon cancer patients than in healthy subjects(24.52±4.56) kg / m2 vs.(23.75±3.14) kg / m2,t=-3.72,P<0.001.When stratified by sex and age, the BMI was always higher in colon cancer patients than in healthy subjects.Logistic regression analyses showed that BMI was an important risk factor of colon cancer(odds ratio =1.059, 95% confidence interval =1.029-1.090).Conclusion:The occurrence of colon cancer in Chinese population is related to BMI.更多还原