Objective To evaluate the clinical efficacy of urethrotomy by using Holmiun laser combined ureteroscopy and cold knife.Methods The clinical data of 46 patients(group A)treated by Holmiun laser combined ureteroscopy and 72 patients(group B)underwent cold knife urethrotomy were retrospectively analyzed.Results In group A,36 cases were followed up for 4~12 months,of whom the average peak urinary flow rate(Qmax)was 16.8±3.2 ml/s,5 cases received reoperation;In group B,51 cases were followed up for 8~25 months,i...