【摘要】 利用Reimer-Tiemann及Vilsmeier反应原理,分别以二苯并-18-冠-6、三氯甲烷(CHCl3)和NaOH或者二苯并-18-冠-6、DMF和POCl3为原料,优化合成了二甲酰基二苯并18-冠-6,克服了直接酰基化使冠醚环断链等缺点,产品收率最高可达78.2%,并通过IR、1HNMR及元素分析等方法对产物进行结构表征。更多还原

【Abstract】 Through the Reimer-Tiemann reaction and the Vilsmeier reaction pripinples,diformyl-dibenzo-18-crown-6 was synthesized under the optimized conditions with dibenzo-18-crown-6,CHCl3 and NaOH or dibenzo-18-crown-6,DMF and POCl3 as raw materials. The method can avoid the ring of dibenzo-18-crown-6 from fragmentation chain. The high yield can reach 78.2%. All the compounds were characterized by IR,1H NMR,Element analysis.更多还原