【摘要】 目的了解孕前妇女TORCH感染情况,对筛查出的风疹病毒抗体阴性者,通过注射风疹疫苗,获得主动免疫后再怀孕,对弓形虫抗体阳性,巨细胞病毒,单纯疱疹病毒及其他病毒感染者,转诊到相关医疗单位进行治疗,以减少缺陷儿的出生。方法采用生物芯片技术对20000例孕前妇女的血清进行TORCH病原体IgM检测。结果TORCH-IgM总阳性1784例、阳性率8.92%,单项病原体感染1395例、阳性率6.98%,合并感染(两种以上病原体)389例、阳性率1.95%。总Tox-IgM阳性419例、阳性率2.09%,RuV-IgM阳性825例、阳性率4.13%,CMV-IgM阳性423例、阳性率2.12%,HSV-I-IgM阳性422例、阳性率2.11%,HSV-Ⅱ-IgM阳性233例、阳性率1.17%。结论孕前妇女TORCH检测对预防宫内感染和畸形胎儿出生,提高出生人口素质具有非常重要的意义,建议将TORCH检测作为孕前常规检查项目。更多还原

【Abstract】 Objective:To understand the prevalence of TORCH infection in pre-pregnant women,so as to provide active immunotherapy to those with negative RV antibodies by RV vaccination,give pre-pregnancy treatment to those infected with TOX,CMV,HSV or other virus and to reduce the number of abnormal fetuses.Methods:Serum samples from 20 000 pre-pregnant women were determined for TORCH special IgM antibodies by microarray technique.Results:The total positive rate of TORCH was 8.92%(1784/20000),while those of TOX,RV,CMV,HSV-I and HSV-II were 2.09%(419/20000),4.13%(825/20000),2.12%(423/20000),2.11% (422/20000) and 1.17%(233/20000),respectively.Conclusion:Pre-pregnancy examination for TORCH infection is of important significance for the prevention of intrauterine infection and abnormal fetuses,as well as for the improvement of the neonatal population quality.更多还原