【摘要】 目的探讨妊娠合并梅毒患者的抗梅毒治疗对妊娠结局的影响。方法对韶关市妇幼保健院2000年1月至2006年12月间,妊娠合并梅毒患者进行回顾性临床分析。根据是否行抗梅毒治疗,将妊娠合并梅毒患者分为治疗组与非治疗组,治疗组患者行青霉素治疗,非治疗组患者未行青霉素治疗。结果7年间医院分娩总人数12650例,接受梅毒筛查者8942例,妊娠合并梅毒患者82例,发生率9.2‰,治疗组与非治疗组新生儿死亡率分别为0及12.5%,先天梅毒分别为24.1%及56.30%,死胎发生率为3.1%及23.3%。结论妊娠期梅毒是危害围产儿的严重合并症:孕期梅毒筛查是诊断的必要手段。孕期有效的青霉素治疗,将降低围产儿死亡率及先天梅毒的发生。更多还原

【Abstract】 Objective:To investigate the effects of treatment of syphilis in pregnancy on perinmal prognosis. Methods:Patients of syphilis in pregancy from Shaoguang Maternal mad Child Health Hospital during 2000.1 to 2006.12 were collected for retrospective analysis.Prepnant wolnen with syphilis were divided into treated group and tmtreated group according to whether mey recived penicillin anti-syphilis treatment or not during pregnancy. Results:The total number of deliveries in the hospital during that period was12650,and 82 out of 8942 women screened for syphilis were positive,giving an incidence of 9.2/1000.The perinatal mortality rates were 0 in treated group and 12.5%in untreateded group,and incidences of congenital syphilis were 24.1% in treated group and 56.3% respectively.Conclusion:Syphilis in pregnancy is a serious complication to harm the fetus.Screening of syphilis during pregnancy is necessary,and penicillin treatment is effective which may reduce the perinatal mortality rate and the birth of congenital syphilis baby.更多还原