【摘要】 目的探讨²⁰¹Tl显像及其半定量分析在软组织良性恶肿瘤诊断中的应用价值。方法回顾性研究骨肿瘤科66例肢体软组织肿瘤及瘤样病变的²⁰¹Tl显像临床资料,利用ROI技术对其进行半定量分析,所有病例均经手术或病理组织学证实。结果²⁰¹Tl双时相显像对肢体软组织肿瘤良恶性诊断的灵敏度,特异性和准确性分别为89.2%（33/37）、82.8%（24/29）、86.4%（57/66）。早期相恶性肿瘤组T/NT^e值为3.02±1.74,明显高于良性肿瘤组（1.62±0.84）（P<0.05）;延迟相恶性肿瘤组T/NT^d值为2.34±1.28,明显高于良性肿瘤组1.26±0.46（P<0.05）。结论²⁰¹Tl双时相显像是一种方便、无创的检查方法。在鉴别软组织良、恶性肿瘤的应用方面具有较高的临床诊断价值。更多还原

【Abstract】 Objective To investigate the value of thallium-201-chloride(²⁰¹T1)scans and semi-quantitative assessment in the differential diagnosis of soft tissue tumors in extremity.Methods ²⁰¹T1 scans was performed in 66 patients with soft tissue tumors.Technique of ROI was used for semi-quantitative assessment.All the cases were confirmed by surgery and histopathological examinations.Results The sensitivity,specificity,and accuracy of ²⁰¹T1 scans were 89.2%,82.8%,and 86.4%,respectively.The early T/NT^e of malignant lesions（3.02±1.74）were higher than benign lesions（1.62±0.84） （P<0.05）.The delay T/NT^d of malignant lesions（2.34±1.28）were higher than benign lesions（1.26±0.46）（P<0.05）.Conclusion These results support the notion that ²⁰¹T1 scintigraphy,although showing some false-positive and false-negative findings,is a useful tool in the evaluation of either malignant tumors or benign lesions.更多还原