【摘要】 目的观察抗病毒治疗代偿期肝炎肝硬化的临床疗效。方法两组均给予保肝及免疫调节治疗,一组加服拉米夫定,每日100mg,连续12个月。另一组应用干扰素300～500万U,其中安达芬21例,运得素9例,疗程6～12个月,治疗后每3个月行上述检测及不良反应观察。结果治疗3个月、6个月、9个月、12个月拉米夫定治疗组和干扰素组两组比较差异有显著性(P<0.05)。拉米夫定治疗组疗效高于干扰素组。结论拉米夫定起效快,抑制病毒作用强,短期内抗病毒疗效显著。更多还原

【Abstract】 Objective Review of the efficacy of anti-retroviral therapy to decompensated cirrhosis. Methods Both groups were given the treatment of liver and immune regulation,a group of lamivudine plus, daily 100mg,for 12 months,the other group of Interferon,300-5000000U,for6-12 months.Detection and adverse reactions were observed every three months.Results There was a significant difference in two groups after 3 months,6 months,9 months,12 months(P< 0.05).The efficacy of lamivudine in the treatment group than the interferon group.Conclusion Lamivudine had strong effect of anti-viral in the short term significantly.更多还原