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2型糖尿病患者糖尿病肾病相关危险因素分析

Analysis over risk factors of diabetic nephropathy in 462 cases with type 2 diabetes mellitus

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【作者】 黄晖刘鹏鹰

【Author】 HUANG Hui,LIU Peng-ying (Department of Endocrinology,The Second People Hospital of Shenzhen City,Shenzhen,Guangdong 518000,P.R.China)

【机构】 广东省深圳市第二人民医院内分泌科广东省深圳市第二人民医院内分泌科 广东深圳518000广东深圳518000

【摘要】 目的探讨2型糖尿病患者糖尿病肾病相关危险因素。方法应用多因素逐步回归的分析方法对380例2型糖尿病患者中186例糖尿病肾病(DN)和276例非糖尿病肾病(non-DN)患者有关危险因素(血压、血糖、胰岛素、三酰甘油及病程等)进行分析。结果DN组与非DN组比较,血压、血糖、胰岛素、三酰甘油、病程明显升高(P<0.05),多元回归分析显示,与DN相关的危险因素为舒张压、收缩压、空腹及餐后血糖、空腹胰岛素、三酰甘油和病程等。结论DN的发生与高血压、高血糖、高胰岛素血症、高血脂及病程相关。

【Abstract】 Objective To study the correlated risk factors of diabetic nephropathy (DN) of type 2 diabetes. Methods 380 cases with type 2 diabetes in our hospital during the period of 2003~2006 were screened for diabetic nephropathy,and its correlated risk factors were analysed by multi-factor converse analyses. Result Through multi-factor converse analyses,We found that the factors in DN group is obviously higher than that of non-DN group in blood pressure,blood sugar,insulin,glycerine trioleate and course of disease (P <0.05). Conclusion Multi-factor converse analyse of this study show that the risk factors related with DN are diastolic pressure,fasting and postprandial plasma glucose,fasting insulin,glycerine trioleate,courses of diseases.

  • 【文献出处】 中国现代医学杂志 ,China Journal of Modern Medicine , 编辑部邮箱 ,2008年08期
  • 【分类号】R587.2
  • 【被引频次】36
  • 【下载频次】205
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