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心肌酶活性和NSE与小儿高胆红素血症的变化及临床意义

Changes of cardiomyoenzyme NSE and their clinical significance in children with hyperbilirubinemia

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【作者】 郑振文李吉昌郝芳郭山春郭晓辉

【Author】 ZHENG Zhen-wen,LI Ji-chang,HAO Fang,et al.People’ s Hospital of Binzhou,Shandong 256610,China

【机构】 山东省滨州市人民医院小儿内科

【摘要】 目的探讨心肌酶活性和NSE与小儿高胆红素血症的变化及临床意义。方法选择住院小儿40例为治疗组,同期来门诊查体的健康小儿20例作为对照组,分别行血清心肌酶及NSE的检测。结果治疗组明显高于对照组(P<0.01),胆红素越高心肌酶及NSE也越高,经治疗1周后,与入院时比较各项指标明显下降(P<0.01)。结论心肌酶活性可以了解高胆患儿对心肌损害的程度;NSE水平可更早、更灵敏地反映其对高胆患儿脑细胞损害的程度,对临床进行早期评估和干预治疗具有重要的指导意义。

【Abstract】 Objective To study the changes of cardiomyoenzyme,NSE and their clinical significance in children with hyperbilirubinemia.Methods Inpatients(n=40)as therapeutic group and healthy children(n=20) as control group were given cardiomyoenzyme and NSE measurement.Results Cardiomyoenzyme and NSE in children with hyperbiliubinemia were higher than that of healthy children.the therapeutic group were higher than the control group(P<0.01).The bilirubin decreased and so did the cardiomyoenzeme and NSE after treatment of one week(P<0.01).Conclusions Cardiomyoenzyme and NSE could response respectively the damage degree of cardiocyte and brain cell in children with hyperbilirubinemia earlier and sensitively;there were important guide significance with the earlier clinical evaluation and intervention treatment.

【关键词】 高胆红素血症心肌酶NSE小儿
【Key words】 HyperbilirubinemiaCardiomyoenzmeNSEChildren
  • 【文献出处】 中国现代药物应用 ,Chinese Journal of Modern Drug Application , 编辑部邮箱 ,2008年24期
  • 【分类号】R725.7;R446.6
  • 【被引频次】2
  • 【下载频次】20
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