【摘要】 目的对加替沙星和左氧氟沙星治疗尿路感染进行成本-效果分析。方法选择就诊的尿路感染患者80例,随机分成两个治疗组:加替沙星组和左氧氟沙星组,运用药物经济学方法对两治疗组进行最小成本-效果分析比较。结果加替沙星组和左氧氟沙星组的有效率分别为92.5%和95.0%,细菌清除率分别为92.6%和85.7%,不良反应发生率分别为3.61%和4.42%,差异均无统计学意义(P>0.05),但成本-效果比分别为83.0和45.5,差异有统计学意义(P<0.05)。结论左氧氟沙星比加替沙星更具成本-效果优势,不失为治疗尿路感染的一种较为安全、有效且经济的选择。更多还原

【Abstract】 Objective To analyze the cost-effect of gatifloxacin and levofloxacin in treatment of urinary tract infection.Methods 80 cases with urinary infection were randomly divided into 2 groups,in which they were treated with gatifloxacin and levofloxacin,respectively.The cost-effect in two groups was analyzed and compared with each other by pharmacoeconomical method.Results There was no significant difference in therapeutic effect between two groups(P>0.05),such as effective rate of 92.5% and95.0%,bacterial clearance rates of 92.6% and 85.7% and undesired event rates of 3.61% and 4.22% in gatifloxacin group and levofloxacin group.However,there was significant difference in cost-effect ratio between two group,83.0 and 45.5 respectively in gatifloxacin group and levofloxacin group(P<0.05).Conclusion Levofloxacin has cost-effect advantage over gatifloxacin in the treatment of urinary tract infection.更多还原