【摘要】 目的应用计算流体力学软件结合有限元法对颅内动脉瘤进行三维数值模拟,分析动脉瘤的血液动力学特性。方法利用临床三维血管造影图像建立动脉瘤数值模型,用Matlab7.0软件及Ansys软件提取动脉瘤的立体轮廓并进行三维网格划分,然后应用Fluent6.02软件进行动脉瘤数值模拟及血流动力学分析。结果本例研究对象显示动脉瘤流入道的血流速度、动压及壁面切应力最高,流出道次之,顶部最低。结论①根据病人的解剖结构所构建的动脉瘤模型的三维数值模拟,把压力入口及脉搏波动应用其中,对血流动力学数据分析更先进、更接近临床实际。②动脉瘤顶部的血流流速、瘤内压力、壁面切应力均最低,这种特殊的结构导致了动脉瘤顶部可能成为动脉瘤破裂的部位。③动脉瘤三维数值模拟能够很好地反应动脉瘤的血液动力学特性,是一种极好的动脉瘤实验及临床研究方法。更多还原

【Abstract】 Objective To simulate the patient-specific aneurismal model with computational fluid dynamic (CFD) software and analyze the characteristic of hemodynamics. Methods A patient-specific model was constructed and the parameters were measured. The images of aneurysms were processed by image processing software (Matlab 7.0). In Ansys, the rigid structure was used to mesh the volume of the aneurysms. Then the computational fluid dynamics software (Fluent 6.02) was used to simulate the blood flow and analyze the hydrodynamics. Results The dynamic pressure, velocity and wall shear stress on the tip of the aneurismal models were lowest. The parameters near the "inflow tract" were highest. Conclusions ①The three dimensional CFD and analysis of the patient-specific models are more practical and advanced. ②The particular structure of the aneurysms results that the tip of the aneurysm is the dangerous region for rupture, and the dynamic pressure, velocity, and wall shear stress in the region are the lowest. ③The three dimensional numerical simulation is a better way in experimental and clinical research because it can indicate the hemodynamics of the aneurysms.更多还原