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张掖市吸毒人员HIV、梅毒、HBV及HCV感染现状调查

Investigation on HIV,syphilis,HBV,HCV infection of drug users in Zhangye City

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【作者】 杜玉桂郑玉梅公洁银万栋邵芙蓉

【Author】 Du Yu-gui1,Zheng Yu-mei1,Gong Jie2,Yin Wan-dong1,Shao Fu-rong1(1.Zhangye Center for Disease Control and Prevention,Zhangye 734000,China;2.Zhangye City Hospital,Zhangye 734000,China)

【机构】 甘肃省张掖市疾病预防控制中心甘肃省张掖市医院

【摘要】 目的:分析张掖市吸毒人员人口学基本特征和行为学特征;了解该人群艾滋病病毒(HIV)、梅毒、乙型肝炎病毒(HBV)表面抗原(HBsAg)、丙型肝炎病毒(HCV)感染现状,为制定控制策略和措施奠定基础。方法:采用统一的吸毒者登记表对吸毒人员进行问卷调查,采集静脉血进行检测。结果:吸毒人员年龄主要集中在31~40岁61.24%(828/1352),年龄最小者17岁,最大者62岁。初中及以下文化程度82.88%,无业者52.30%,未婚者48.73%。静脉吸毒者22.2%,静脉吸毒共用针具比例33.90%,通过钱或毒品与他人发生性关系者19.10%,且从未使用安全套者高达59.11%。血清学监测结果显示:H IV抗体、梅毒、HBsAg、抗-HCV阳性率分别为0.15%,3.91%,11.15%,19.29%。抗-HCV阳性率由2004年的16.56%上升至2007的23.45%,呈逐年上升趋势(2χ=12.73,P<0.01)。114份抗-HCV阳性血清HCVRNA阳性66份,阳性率57.89%。结论:该人群高危行为突出,是艾滋病性病传播的桥梁人群,也是采取干预措施的重点人群,当务之急应继续扩大美沙酮门诊工作规模,迅速扩大治疗覆盖面,让更多的吸毒人员接受美沙酮替代治疗,同时大力推广针具交换,开展转介服务,以遏制H IV、梅毒、HBV、HCV在该人群中的进一步扩散蔓延。

【Abstract】 Objective:Zhangye City drug addicts basic demographic characteristics and behavioral characteristics of a better understanding of the population of HIV(HIV),syphilis,hepatitis B virus(HBV) surface antigen(HBsAg),hepatitis C virus(HCV) infection status quo,to develop control strategies and measures to lay the foundation.Methods:Reunification of the registration form for drug addicts officers conducted a questionnaire survey,collected blood for testing.Results:Drug users aged 31~40 years mainly concentrated in 61.24%(828/1352),the youngest 17 years old,those who are 62 years old.Education level below junior high school and 82.88%,52.30 percent are unemployed,unmarried persons 48.73%.Intravenous drug users 22.2%,injection drug users sharing needles a proportion of 33.90%,through drug money or have sexual relations with others,19.10%,and never use condoms to high Up 59.11%.Serological monitoring results indicate that: HIV antibodies,syphilis,HBsAg,anti-HCV-positive rate was 0.15%,3.91%,11.15%,19.29%.Anti-HCV-positive rate from 2004′s 16.56 percent rise to 23.45 percent in 2007,showed an upward trend year by year(χ2 = 12.73,P<0.01).114-HCV positive serum HCVRNA positive 66,the positive rate of 57.89 percent.Conclusion:The crowd prominent high-risk behavior,is the spread of AIDS and venereal disease bridge the crowd,is also the focus of interventions crowd,top priority should continue to expand the scale of the methadone clinic,the rapid expansion of coverage,so that more drug addicts receiving methadone replacement therapy,To promote needle exchange,for referral services,to curb HIV,syphilis,HBV,HCV in the crowd of further spread.

  • 【文献出处】 中国卫生检验杂志 ,Chinese Journal of Health Laboratory Technology , 编辑部邮箱 ,2008年12期
  • 【分类号】R181.3
  • 【被引频次】15
  • 【下载频次】94
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