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857例临床感染的常见菌及其对抗菌药物的敏感性

Common bacteria and their antibiotic sensitivity in 857 cases of infection

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【作者】 许敏闫广杰

【Author】 Xu Min1,Yan Guang-jie2 (1.Dongling Center for Disease Control and Prevention,Shenyang 110015,China;2.Shenhe Center for Disease Control and Prevention,Shenyang 110011,China)

【机构】 沈阳市东陵区疾病预防控制中心沈阳市沈河区疾病预防控制中心 沈阳110015沈阳110011

【摘要】 目的:探讨临床感染的病原菌种类及其对抗菌药物的敏感性,指导临床合理应用抗菌药物。方法:收集住院与门诊病人血液、尿液、痰、分泌物等标本,进行细菌分类培养、鉴定,对分离出的主要病原菌做药敏试验。结果:857例病人标本分离出革兰阴性杆菌607株(66.9%)、革兰阳性球菌97株(10.7%)、酵母菌195株(21.5%)、其他阳性菌株9株(1.0%),革兰阴性菌以克雷伯菌属、大肠埃希菌属、铜绿假单胞菌、不动杆菌属、沙雷菌属为主;革兰阳性球菌以表皮葡萄球菌、金黄色葡萄球菌、肠球菌、肺炎链球菌为主。实验亚胺南对革兰阴性杆菌的作用很强;去甲万古霉素对革兰阳性球菌的敏感率达100%,其他抗菌药物存在不同程度的致病性和耐药性。结论:病原菌的种类在发生变迁,耐药性日益严重,提示临床医生要合理应用抗菌药物,加强实验室的感染监控职能,开展耐药监测。

【Abstract】 Objective:To investigate the variety of clinical infection pathogenic bacterium and that for the sensitivity of antibacterial.To direct clinical reasonable makes use of antibacterial.Methods:Collected the samples of blood,urine,phlegm,and excreta with patients in hospital and outpatients.To carry out bacterium grouping cultivating,appraisement,and did the susceptibility test of main pathogenic bacterium which were isolated.Results:The samples from 857 patients were isolated Gram-Negative bacilli 607 strains(66.9%),Gram-Positive bacilli 97 strains(10.7%),fermentum 195 strains(21.5%) and other positive strains 9 strains(1.0%).Gram-Negative bacilli were mainly of Klebsiella,Escherichia coli,Pseudomonas aeruginosa,Acinetobacter and Serratia.Gram-Positive bacilli were mainly of Staphylococcus epidermidis,Staphylococcus aureus,Enterococci and Streptococcus pneumoniae.Imipenem was make powerful effect for Gram-Negative bacilli;the rate of sensitivity of norvancomycin for Gram-Positive bacilli was 100%,and different degrees of pathogenicity and drug resistance for other antibacterial.Conclusion:The variety of pathogenic bacterium is happen diversely,drug resistance is increasing serious,which hints clinician using antibacterial reasonability.Enhance breadboard infection monitoring functional authority.Develop drug fast monitoring.

【关键词】 病原菌抗菌药物敏感性
【Key words】 Pathogenic bacteriumAntibacterialSensitivity
  • 【文献出处】 中国卫生检验杂志 ,Chinese Journal of Health Laboratory Technology , 编辑部邮箱 ,2008年06期
  • 【分类号】R446.5
  • 【被引频次】1
  • 【下载频次】23
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