【摘要】 目的:了解温岭地区食品、公共场所从业人员乙肝血清学标志物的感染情况。探讨在健康人群中乙肝病毒血清标志物的表现模式及其构成比,不同模式的传染性及流行病学意义,为食品、公共场所从业人员乙型肝炎体检及其管理提供科学依据。方法:对2006年温岭市19301例食品、公共场所从业人员血清用EILISA方法检测乙肝5项指标,在18种模式中抽取11种模式检测HBV DNA,确定其传染性和流行病学意义。结果:19301份血清标本检出HBV血清标志物8685份,总感染率45.0%。同时组成18种血清学模式,其中"145"、"135"、"15"、"1235"、"25"、"245"模式的HBV DNA阳性率分别达46.9%、93.8%、50.0%、100.0%、8.1%和5.0%。结论:温岭市食品、公共场所从业人员乙肝5项指标检测结果反映,在同类人群中血清总感染率偏高,除"135"组具有传染性外,其它模式也存在一定的传染性,且所占比例较大。为了有效地减少传染源,切断传播途径,建议对其它模式开展HBV DNA等先进方法检测其传染性,并在法律上明确凡是具有传染性的从业人员禁止其上岗,以减少乙肝的传染源。更多还原

【Abstract】 Objective:To investigate infection situation of hepatitis B serology symbol of jobholder serving for food and public place in Wenling City and determine performance pattern and its constitution ratio of hepatitis B serology symbol in healthy crowd as well as infectivity and epidemiological significance of different pattern,and provide scientific basis for hepatitis B examination and its management of jobholders serving for food and public place.Methods:Detect hepatitis B′s five targets in blood serum of 19301 jobholders serving for food and public place in Wenling City in 2006 with EILISA,and then detect HBV DNA in eleven patterns of eighteen patterns,and definite their infectivity and epidemiological significance.Results:Check out 8685 portions HBV serological symbol in 19301 portions of blood serum sample,and the total infection rate was 45.0%.The HBV DNA positive rate of "145","135","15","1235","25","245" pattern was separately 46.9%,93.8%,50.0%,100.0%,8.1% and 5.0%.Conclusion:Hepatitis B′s total infection rate in blood serum is on the high side compared with the same crowd,according to the examination results of jobholder serving for food and public place in Wenling City.All the patterns have certain infectivity accounting for the proportion to be bigger,except for "135"pattern.To reduce the number of origin of infection and cut the route of transmission,the examination of all patterns which have certain infectivity with advanced methods such as HBV DNA should be done,Meanwhile,prohibit every jobholders who have HBV infectivity serving for food and public place no more in law.更多还原