【摘要】 目的探讨2型糖尿病患者血清超敏C-反应蛋白(hs-CRP)水平及与糖化血红蛋白(GSB)、总胆固醇(TC)、总胆固醇(TC)/高密度脂蛋白胆固醇(HDL-C)的关系。方法采用德国BN-Prospec特定蛋白仪、伯乐DiaSTAT糖化血红蛋白仪、日立OLYMPUS2700生化分析仪对56例2型糖尿病患者及40例健康对照的hs-CRP、GSB、TC、TC/HDL-C进行测定。56例2型糖尿病患者被分成为两组:A组无临床并发症(包括视网膜病变、肾病及神经障碍);B组至少有一种临床并发症。结果56例2型糖尿病患者hs-CRP比40例健康对照明显升高(P<0.001),在2型糖尿病组中B组hs-CRP比A组明显升高(P<0.001),且与GSB、TC、TC/HDL-C正相关。结论hs-CRP可作为2型糖尿病并发症出现的风险预测指标。更多还原

【Abstract】 Objective To investigate the levels of serum high-sensitive C-Reactive Proteins(hs-CRP)in type 2 diabetes(T2DM),and the relationship of high-sensitivity C-reactive protein(hsCRP)and glycosylated hemoglobin(GSB)、total choleslerol(TC),ratio of total choleslerol(TC)/high density lipoprotein choleslerol(HDL-C,TC/HDL-C).Methods Hs-CRP and GSB,TC,TC/HDL-C in 56 patients of T2DM and 40 health controls were measured by BN-Prospec、DiaSTAT,OLYMPUS2700.56 patients in T2DM were divided into to 2 groups:A group had no complication(retinopathy、nephrosis and neurological disorder);B group had at least a clinical complication.Results The serum hs-CRP in the 56 patients of T2DM was higher than those of 40 health controls(P<0.001),B group was higher than A group(P<0.001).Hs-CRP is positively correlated with GS,TC,TC/HDL-C.Conclusion Hs-CRP is regarded as a marker to estimate the risk of complication of T2DM.更多还原