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胰岛素泵强化治疗2型糖尿病的临床价值

The insulin pump strengthens treats type 2 diabetes clinical value

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【作者】 龚敏

【Author】 GONG Min.Department of endocrinology,Nanhui Central Hospital,Shanghai 201300,China

【机构】 上海市南汇区中心医院内分泌科

【摘要】 目的探讨胰岛素泵强化治疗2型糖尿病的临床价值。方法将134例2型糖尿病患者分为连续皮下注射胰岛素(continuous subcutaneous insulin infusion,CSⅡ,n=70)和每天多次皮下注射胰岛素(multiple subcutaneous insulin injection,MSⅡ,n=64)。CSⅡ组将短效胰岛素置于胰岛素泵内持续皮下注射,进餐前再按所需输入负荷量;MSⅡ组将短效胰岛素装入普通注射器内于每天三餐前及22:00皮下注射,治疗2周后对两组的疗效进行比较。结果2种方法均可使患者的血糖达标。CSⅡ组血糖达标所需时间为(6·5±1·3)d,MSⅡ组所需时间为(10·1±2·1)d;CSⅡ组血糖达标所需胰岛素用量为(36·1±7·3)U/d,MSⅡ组血糖达标所需胰岛素用量为(42·7±6·9)U/d,CSⅡ组低血糖发生次数为0·03次/(d·人),MSⅡ组低血糖发生次数为0·08次/(d·人)。两组上述指标比较差异均有统计学意义,均为P<0·05。结论CSⅡ能更快速地控制2型糖尿病患者的血糖,所需胰岛素用量较少,低血糖发生率较低。

【Abstract】 Objective The discussion insulin pump strengthens treats type 2 diabetes clinical value.Methods Divides into continuous subcutaneous insulin infusion(CSII,n=70)and each multiple subcutaneous insulin injection(MSⅡ,n=64)134 examples type 2 diabetes.The CSⅡ group puts in the short effect insulin in the insulin pump to continue the hypodermic injection,before dining,presses again must input the load;The MSⅡ group loads short effect insulin in the ordinary injector before every 3 meals and 22:00 hypodermic injection.Treats 2 weeks later carries on the comparison to 2 groups of curative effects.Results 2 methods may cause patient’s blood sugar to attain a designated standard.The CSⅡ group blood sugar standards need(6.5±1.3)days,The MSⅡ group institute need(10.1±2.1)days;The CSⅡgroup blood sugar standards needs the insulin amount used for(36.1±7.3)U/d,The MSⅡ group blood sugar standards needs the insulin amount used for(42.7±6.9)U/d,The CSⅡgroup hypoglycemia has the number of times 0.03 time/(Day. person),The MSⅡ group hypoglycemia has the number of times is 0.08 time/(Day.Person).2 groups of above target comparison difference have statistics significance,is P<0.05.Conclusion CSⅡCan control type 2 diabete’s blood sugar fast,uses few insulin,with low rate of the hypoglycemia.

【关键词】 糖尿病胰岛素强化治疗
【Key words】 DiabetesInsulinStrengthened treatment
  • 【文献出处】 中国实用医药 ,China Practical Medicine , 编辑部邮箱 ,2008年15期
  • 【分类号】R587.1
  • 【被引频次】2
  • 【下载频次】52
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