【摘要】 目的利用功能磁共振成像(fMRI)探讨前扣带回与创伤后应激障碍(PTSD)之间的关系。方法对12例符合美国精神障碍诊断与统计手册第4版(DSM-IV)的创伤后应激障碍患者和12名正常对照进行可以针对性激活前扣带回的Stroop色词测验,并对其行fMRI扫描,分析两组之间前扣带回激活信号强度的差异。结果患者组前扣带回激活的血氧依赖水平(BOLD)的信号明显弱于对照组,差异有统计学意义(P<0.05)。结论前扣带回与创伤后应激障碍存在着密切的关系。更多还原

【Abstract】 Objective To explore the relationship between the anterior cingulate cortex (ACC) and posttraumatic stress disorder (PTSD). Methods Stroop task was performed in 12 patients with PTSD and 12 normal controls and blood oxygen level-dependent (BOLD) signals were detected using functional MRI. Results Compared with the control group, PTSD group had significantly lower level of BOLD signals in the insular (P<0.05, uncorrected). Conclusions There is a strong relationship between ACC and PTSD.更多还原