【摘要】 目的了解开封农村地区婴幼儿的甲型肝炎抗体水平及动态变化,为疫苗接种提供参考。方法随机抽取该地区569名7~30月龄的婴幼儿,进行甲肝抗体定性及定量检测,分析不同月龄组的抗体水平。结果被调查婴幼儿7~10月时抗体阳性率均在30%以上,之后逐渐下降,13~18月时降至最低之后缓慢上升。7~10月龄抗体阳性率显著高于13~18月龄(P<0.05)。结论该地区婴幼儿甲肝疫苗免疫的最佳时间应为13~18月龄。更多还原

【Abstract】 Objective To explore the titer level and changing tendency of infants’ anti-HAV antibody in rural area of Kaifeng city.Methods 569 healthy children aged 7-30 months were randomly selected.Total anti-HAV antibodies were assayed and quantified,and then the antibody levels were compared and analyzed among different age groups.Results The positive rates were highest in 7~10 month-group(all>30%),and declined in 13-18 month-groups,and then raised slowly in 19~30 month-group.There were significant differences among 7-10 and 13-18 month groups(P<0.05).Conclusion The optimal age for HAV immunization in this area is 13-18 months.更多还原