【摘要】 【目的】研究成年绒山羊次级毛囊组织形态的周期性变化过程,为研究绒山羊绒毛生长的分子调控机理奠定组织学基础。【方法】制作内蒙古绒山羊1年周期内每个月的皮肤组织切片,染色后显微镜下观察照相。【结果】成年绒山羊次级毛囊形态在一年中呈周期性变化,在兴盛期、退行期和休止期的形态各不相同。从4月份开始,次级毛囊外根鞘细胞向下分裂延伸,开始了毛囊的重建;8～9月份毛囊完成重建,毛囊结构完整;10月份毛球细胞停止分裂,毛乳头萎缩,大量细胞程序化死亡,毛根上移,毛囊进入退行期;12月份毛囊根部上升到皮脂腺附近不再变化;翌年1～3月毛囊的形态基本没有变化。【结论】了解了成年绒山羊次级毛囊1年内形态的周期性变化过程,为绒山羊绒毛相关领域的研究提供一定的借鉴。更多还原

【Abstract】 【Objective】 The objective of this study was to observe the secondary follicle cycling of cashmere goat, reveal the molecule regulation of the growth of the cashmere. 【Method】 The skin slices of the adult Inner Mongolian cashmere goats were made each month in a whole year and were further photographed under light microscope after staining. 【Result】 The histomorphology of the secondary follicle of adult cashmere goat showed a periodic change within a year, and it is different in anagen, catagen and telogen. It was observed from vertical slip and longitudinal slip in April; the cells of the secondary follicles ORS regenerate, and grow down into the dermis, the hair follicles start reconstruction. The secondary follicles finish the reconstruction from August to September, and most of them enter into catagen in October. In October, the bulbar epithelial cells’ divisions ceased, and the papilla shrinks accompanied with massive epithelial cells apoptosis in hair follicles. Gradually the hair follicle moved upward, till it reaches the region nearby sebaceous gland in December and no longer vary.【Conclusion】This study illustrates the cycling of the secondary hair follicle of the adult goat and has provided more information about the cashmere goat research field.更多还原