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电针头穴对人脑运动功能区糖代谢影响的正电子发射断层扫描研究

Effects of Electroacupuncture at Head Points on Glucose Metabolism of Cerebral Motor Function Regions in Normal Subjects and Stroke Patients:A Positron Emission Tomography Study

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【作者】 左芳石现田嘉禾姚树林

【Author】 ZUO Fang,SHI Xian,TIAN Jia-he,et al.TCM and Acupuncture & Moxibustion Department of Nanlou,General Hospital of the PLA,Beijing 100853,China

【机构】 中国人民解放军总医院南楼中医针灸科中国人民解放军总医院针灸科中国人民解放军总医院核医学科中国人民解放军总医院核医学科 北京市100853北京市100853

【摘要】 目的研究针刺百会、曲鬓穴对大脑运动功能区糖代谢的影响。方法采用Talairach大脑立体定位法,运用正电子发射断层扫描(PET)观察运动状态下正常人和脑卒中患者电针前后大脑细胞葡萄糖代谢的变化。结果正常人针刺后双侧大脑顶上小叶、楔前叶葡萄糖代谢增高,以左侧大脑为主;患者双侧第一躯体运动皮质区、运动前区及顶上小叶和健侧的补充运动区发生了明显的代谢功能改变,表现为糖代谢增高的区域集中于健侧,代谢减低集中于病灶侧。结论针刺百会与曲鬓穴可以改变大脑双侧有关运动区域的代谢,从而可能诱导与运动相关的某些区域神经组织兴奋,补偿或协助受损的神经网络,促进运动功能的重建。

【Abstract】 Objective To investigate the effect of electroacupuncture on glucose metabolism of the cerebral motor function regions in normal subjects and stroke patients.Methods The glucose metabolism of cerebral motor area in normal subjects and stroke patients before and after acupuncture at Baihui(GV20)and left Qubin(GB7)during the movement were observed with positron emission tomography(PET).Results Acupuncture could increase metabolism of glucose in bilateral superior parietal lobule(LPs)and precuneus,especially in the left among the healthy subjects.For the stroke patients The similar changes of metabolic were observed in the first somastic motor cortical region(MI),premotor cortex(PMC),LPs bilaterally,as well as the supplementary motor area(SMA)of healthy side after acupuncture.Conclusion Acupuncture at Baihui(GV20)and Qubin(GB7)can regulate the glucose metabolism in cerebral structures related to motor function in the bilateral cerebral hemispheres,which may systematically induce excitement of motor nerve,expiate or assist the injured nerve network and expedite the reestablishment of the cerebral motor function.

【基金】 国家中医药管理局资助项目(2002-J-P-47)
  • 【文献出处】 中国康复理论与实践 ,Chinese Journal of Rehabilitation Theory and Practice , 编辑部邮箱 ,2008年03期
  • 【分类号】R245.97
  • 【被引频次】24
  • 【下载频次】113
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