【摘要】 目的探讨谷氨酰胺联合肠内营养对动物模型结肠粘膜的影响。方法将大鼠随机分为4组,即模型肠内营养组,谷氨酰胺大剂量+肠内营养组,谷氨酰胺中剂量+肠内营养组,谷氨酰胺小剂量+肠内营养组。分为7天、14天两个时间点进行观察。结果Gln各组肠壁肌层增厚明显,皱襞明显增高,肠腺数量增多,其中大、中剂量组的皱襞不仅高且密集,皱壁高度、肠腺密度均明显大于模型组(P<0.01)。结论谷氨酰胺+肠内营养比单用肠内营养更可以促进大鼠结肠的代偿,且大、中剂量组优于小剂量组。更多还原

【Abstract】 Objective To detect the influence of glutamine combined with enteral nutrition to rat model colon mucosa.Methods Rat have been divided into 4 groups,that is model EN group,large,middle,small dose of Glutamine +EN group,which were observed at the 7th,14th day.Results Plica of Every group of Glutamine andcrypts of Lieberkuhn increased obviously,large,middle dose of Glutamine +EN group have significant difference with model group.Conclusion Glutamine group may enhance compensation of colon mucosa of rat.更多还原