【摘要】 目的以左氧氟沙星注射液为对照,采用随机对照、多中心、平行开放的实验设计,评价莫西沙星治疗敏感菌引起的临床感染的有效性和安全性。方法盐酸莫西沙星注射液用法用量为400mg,qd,静滴,乳酸左氧氟沙星注射液用法用量为400mg,qd,静滴,疗程均为7～14天。患者总例数为49例。结果试验组和对照组的临床有效率分别为96.30%和77.27%;不同菌种感染患者的临床有效率分别为95.65%和73.68%;细菌清除率分别为95.65%和78.95%;不良反应发生率分别为14.81%和27.27%。结论盐酸莫西沙星注射液是治疗临床感染安全有效的药物。更多还原

【Abstract】 Objective A ranelonized controuled,multi-center,open parallel experimental design,to evaluate the efficacy and safety of moxifloxacin ivtreatment of infections caused minganjun. Compared to ciprofloxacin iv. Methods The dose of moxifloxacin iv and levofloxacin iv were 400mg,qd and duration of treatment was 7～14 days. The total number of cases to 49. Results Experimental group and control group respectively,the clinical efficiency was 96.3% and 77.27%; Different strains of the infected pctients were clinical efficienly were 95.65%和73.68%; Bacterial cleerance rates were 95.65% and 78.95%; Adverse reaction rates were 14.81% and 27.27%. Conclusion It is concluded that moxifloxacin iv has an excellent clinical efficacy and good safety profile in treating patients with bacterial infections.更多还原