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红花化学成分研究

Chemical constituents from flowers of Carthamus tinctorius

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【作者】 姜建双夏鹏飞冯子明张培成

【Author】 JIANG Jian-shuang,XIA Peng-fei,FENG Zi-ming,ZHANG Pei-cheng(Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine,Institute of Materia Medica,Peking Union Medical College and Chinese Academy of Medical Sciences,Beijing 100050,China)

【机构】 中国医学科学院中国协和医科大学药物研究所中草药物质基础与资源利用教育部重点实验室

【摘要】 目的:研究红花Carthamus tinctorius的化学成分。方法:通过各种柱色谱进行分离纯化,根据理化性质和波谱数据进行结构鉴定。结果:分离并鉴定了10个化合物:7,8-dimethylpyrazino[2,3-g]quinazolin-2,4-(1H,3H)-dione(1),腺苷(2),腺嘌呤(3),尿苷(4),胸腺嘧啶(5),尿嘧啶(6),roseoside(7),4′-O-二氢红花菜豆酸-β-D-葡萄糖苷甲酯(8),4-O-β-D-吡喃葡萄糖氧基苯甲酸(9)和对羟基苯甲酸(10)。结论:化合物1和8为首次得到的天然产物,化合物7,9,10为首次从红花中分离得到。

【Abstract】 Objective:To study the chemical constituents from the flowers of Carthamus tinctorius.Method: Compounds were isolated by chromatographic techniques.Their structures were elucidated by spectral methods.Result: Ten compounds were identified as 7,8-dimethylpyrazinoquinazolin-2,4-(1H,3H)-dione(1),adenosine(2),adenine(3),uridine(4),thymine(5),uracil(6),roseoside(7),4′-O-dihydrophaseic acid-β-D-glucopyranoside methylester(8),4-O-β-D-glucopyranosyloxy-benzoic acid(9) and p-hydroxybenzoic acid(10).Conclusion: Compounds 1 and 8 were isolated from natural plants for the first time,and compounds 7,9 and 10 were isolated from this plant for the first time.

【基金】 国家自然科学基金项目(30672610)
  • 【文献出处】 中国中药杂志 ,China Journal of Chinese Materia Medica , 编辑部邮箱 ,2008年24期
  • 【分类号】R284
  • 【被引频次】70
  • 【下载频次】1805
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