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地钱化学成分研究

Studies on Chemical Constituents of Marchantia polymorpha L.

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【作者】 方磊牛冲娄红祥

【Author】 FANG Lei,NIU Chong,LOU Hong-xiang(School of Pharmaceutical Sciences,Shandong University,Jinan 250012,China)

【机构】 山东大学药学院山东大学药学院 济南250012济南250012

【摘要】 目的研究地钱(Marchantia polymorpha L.)的化学成分。方法通过多种色谱手段,对地钱的脂溶性成分进行分离。根据化合物的波谱数据进行结构鉴定。结果从地钱中分离得到9个化合物,7个何伯烷型三萜:22-hydroxyhopane(Ⅰ),17(21)-hopene(Ⅱ),6α,22-dihydroxyhopane(Ⅲ),20α,22-dihydroxyhopane(Ⅳ),21,22-dihydroxyhopane(Ⅴ),6α,11α,22-tri-hydroxyhopane(Ⅵ),22,28-didroxyhopane(Ⅶ);β-谷甾醇(Ⅷ),胡萝卜苷(Ⅸ)。结论化合物Ⅰ~Ⅸ均为首次从本植物中分离得到。

【Abstract】 OBJECTIVE To study the chemical constituents of Marchantia polymorpha L..METHODS Compounds were isolated with various chromatographic techniques,and their structures were elucidated by spectral analysis.RESULTS Nine compounds were obtained and identified as 22-hydroxyhopane(Ⅰ),17(21)-hopene(Ⅱ),6α,22-dihydroxyhopane(Ⅲ),20α,22-dihydroxyhopane(Ⅳ),21,22-dihydroxyhopane(Ⅴ),6α,11α,22-trihydroxyhopane(Ⅵ),22,28-didroxyhopane(Ⅶ),β-sitisterol(Ⅷ) and daucosterol(Ⅸ) respectively.CONCLUSION Compound Ⅰ~Ⅸ were isolated from the plant for the first time.

【关键词】 地钱化学成分三萜何伯烷
【Key words】 Marchantia polymorpha L.chemical constituentstriterpenoidshopane
【基金】 国家自然科学基金资助项目(30271537)
  • 【文献出处】 中国药学杂志 ,Chinese Pharmaceutical Journal , 编辑部邮箱 ,2008年01期
  • 【分类号】R284
  • 【被引频次】8
  • 【下载频次】388
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