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头皮脂溢搽剂制备工艺研究

Preparation Technology of Chinese Traditional Medicine Seborrhea Liniment

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【作者】 董彦富祁梅杨立伦余利军贾海

【Author】 DONG Yan-fu,QI Mei,YANG Li-lun,YU Li-jun,JIA Hai(Dept.of Pharmacy,Gansu Provincial People’s Hospital,Lanzhou 730000,China)

【机构】 甘肃省人民医院药剂科

【摘要】 目的:研究头皮脂溢搽剂的制备工艺。方法:采用正交试验设计L9(34),以60%乙醇为溶剂,以盐酸小檗碱含量为考察指标,以提取方法、提取时间、溶剂用量和提取次数为考察因素,确定最佳制备工艺。结果:最佳制备工艺为采用浸渍法,提取时间为48h,60%乙醇用量1500mL,提取次数为2次。结论:本工艺稳定、可行,可为头皮脂溢搽剂的工业化生产提供理论依据。

【Abstract】 OBJECTIVE:To study the preparation technology of Chinese traditional medicine Seborrhea liniment.METHODS:The preparation technology of Seborrhea liniment was optimized by orthogonal experiment design L9(34)using 60% alcohol as solvent with the content of Berberine hydrochloride as index for evaluation and with the extraction method,extraction time,amount of solvent and number of extraction times as factors.RESULTS:The optimum preparation technical conditions were as follows:by impregnating method,the extraction time was 48 h using 1 500 mL alcohol and the extraction frequency was 2 times.CONCLUSION:The preparation technology of Chinese traditional medicine Seborrhea liniment is stable and feasible,and it serves as a theoretical basis for the industrial production.

  • 【分类号】TQ461
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