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血必净注射液与头孢哌酮钠/舒巴坦钠协同治疗脓毒症的临床观察
Synergetic Effect of Xuebijing Injection and Cefoperazone Sodium/Sulbactam Sodium on Sepsis
【摘要】 目的:观察和评价血必净注射液与注射用头孢哌酮钠/舒巴坦钠协同治疗脓毒症的临床疗效。方法:随机将脓毒症患者分为对照组(75例)与治疗组(79例)。对照组静脉滴注头孢哌酮钠/舒巴坦钠3g,每日2次;治疗组先静脉滴注头孢哌酮钠/舒巴坦钠3g,再静脉滴注血必净注射液100mL,每日2次。7d为1个疗程。结果:治疗组与对照组总有效率分别为94.94%、86.67%,2组有显著性差异(P<0.05)。结论:血必净注射液与头孢哌酮钠/舒巴坦钠协同治疗脓毒症,能够缩短疗程,改善临床症状,提高疗效。
【Abstract】 OBJECTIVE: To observe the synergetic effect of Xuebijing injection and Cefoperazone Sodium/Sulbactam Sodium for the treatment of patients with sepsis.METHODS: Patients with sepsis were randomly assigned to receive Cefoperazone Sodium/Sulbactam Sodium 3 g bid alone by iv drip(Control Group,75 cases) or in combination with Xuebijing injection(100 mL bid,79 cases) for 7 days.RESULTS: The total efficective rate after 7-day treatment had significant difference between two groups(86.67% in control group versus 94.94% in treatment group,(P<0.05).CONCLUSION: The addition of Xuebijing injection to Cefoperazone Sodium/Sulbactam Sodium significantly reduced the course of treatment for the sepsis disease,improved clinical symptoms and increased the curative effect.
【Key words】 Xuebijing injection; Cefoperazone sodium/sulbactam sodium; Sepsis; Synergetic effect;
- 【文献出处】 中国药房 ,China Pharmacy , 编辑部邮箱 ,2008年20期
- 【分类号】R459.7
- 【被引频次】14
- 【下载频次】154