【摘要】 目的:评价肺表面活性物质(PS)治疗婴幼儿体外循环后急性呼吸窘迫综合征(ARDS)的有效性。方法:选取ARDS的婴幼儿患者20例,随机均分成2组。2组均常规治疗,治疗组加用PS,观察2组临床疗效。结果:治疗组死亡率明显比对照组低(P<0.05),有效率比较差异有统计学意义(P<0.05)。治疗组肺动态顺应性和氧合指数明显改善(P<0.05),机械通气时间和ICU住院时间明显缩短(P<0.05)。结论:PS可有效治疗体外循环后ARDS。更多还原

【Abstract】 OBJECTIVE:To evaluate the efficacy of pulmonary surfactan (PS) in the treatment of acute respiratory distress syndrome (ARDS) in infants after undergoing cardio-pulmonary bypass. METHODS: Twenty ADRS infants were randomly assigned to receive routine therapy alone (control group) or routine therapy in combination with PS (trial group). The clinical efficacy in two groups was monitored. RESULTS: In the trial group compared with the control group, the mortality rate was significantly lower(P<0.05), the pulmonary dynamic compliance and oxygenation index improved more significantly(P< 0.05),and the average mechanical ventilative supporting time and the length of stay in ICU were significantly shorter(P< 0.05).CONCLUSION: Pulmonary surfactant is effective for ARDS infants after undergoing cardio-pulmonary bypass.更多还原