【摘要】 目的介绍糖尿病慢性炎性脱髓鞘性周围神经病的临床、电生理特点以及诊断规律。方法4例年龄在37～58岁,2型糖尿病病程为3～9年,出现逐渐进展的肢体无力和感觉障碍的患者,行电生理和脑脊液检查。结果4例患者的脑脊液细胞数目正常,脑脊液蛋白在0.6～2.1g/L之间,呈蛋白细胞分离现象;4例均有感觉神经传导速度下降,其中2例有动作电位波幅下降;运动神经动作电位波幅1例下降,传导速度3例下降;1例的部分感觉、运动神经传导速度未引出;3例患者的H反射和F波均出现下降。结论4例患者的临床表现均存在明显的运动功能障碍。神经传导速度减慢提示存在脱髓鞘改变,脑脊液蛋白细胞分离更有利于该病的诊断。更多还原

【Abstract】 Objective To analyze the clinical characteristics,diagnosis and differential diagnosis of diabetes mellitus-chronic inflammatory demyelinating polyneuropathy.Methods The age of the four cases was between 37-58 years old when they visited us.The duration of type 2 diabetes mellitus was 3-9 years.The patients manifested the progressive weakness of limbs with sensory disturbance.Results The electrophysiological examination showed impairment of both axon and myelin.The CSF showed albuminocytolgoic dissociation in the 4 patients.Variant degree of involvement of H reflex and F wave was observed.Conclusions All four patients manifest obvious motor dysfunction.Though the decrease of nerve conduction velocity is the characteristic of demyelination,the albuminocytolgoic dissociation of CSF are important for the diagnosis.更多还原