2型糖尿病患者脂联素与胰岛素抵抗相关性研究

【摘要】 目的:探讨2型糖尿病脂联素与胰岛素抵抗的相关性。方法:选取2型糖尿病患者138例,分为非肥胖组68例,肥胖组70例。正常对照组:共80例,其中正常非肥胖者40例,正常肥胖者40例。采用酶免法(ELISA)测定血清脂联素,并分析其与胰岛素抵抗的相关性。结果:2型糖尿病组空腹血糖(FPG)、空腹胰岛素(FINS)、胰岛素抵抗指数(HOMA-IR)高于对照组,脂联素水平低于对照组。肥胖组BMI、空腹胰岛素、HOMA-IR、脂联素水平低于非肥胖组。结论:FPG、FINS、BMI、脂联素是影响2型糖尿病胰岛素抵抗的主要危险因素。更多还原

【Abstract】 Objectiv:To explore the relationship of adiponectin’s level with insulin resistance in patients with type 2 diabetes mellitus(DM2).Methods:Select 138 patients with DM2,divided into 68 cases of non-obese group,70 cases of obesity group.The normal non-obese 40 cases,40 cases of normal obesity as Control group.Adiponectin were measured by ELISA,To analysis the relationship of insulin resistance.Results:Fasting plasma glucose(FPG),blood lipids and fasting insulin(FINS),insulin resistance index(HOMA-IR)in DM2 patients were significantly higher than those in Control group.The level of adiponectin was significantly lower than that in the control group.BMI,fasting insulin,HOMA-IR was higher than non-obese group,adiponectin levels lower than non-obese group.Conclus-ions FPG,FINS,BMI,adiponectin,was major risk factors in the impact of type 2 diabetes insulin resistance.更多还原