【摘要】 目的探讨青少年高血压与代谢综合征(MS)各组分之间的关系及其危险因素分析。方法通过分层整群随机抽样,共抽取12～18岁青少年3953人,以12～15岁为青春前期(n=1698),16～18岁为青春期(n=2255),测量身高、体质量、腰围、臀围、血压、空腹血糖(FPG)、三酰甘油(TG)、胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)及低密度脂蛋白胆固醇(LDLC)水平。结果1)总调查人群中高血压患病率为6.2%。2)13～18岁超重肥胖者血压高于体质量正常者(P<0.05)。3)男、女性青春期舒张压(DBP)异常检出率均高于青春期前(P<0.05),青春期女性收缩压(SBP)异常检出率高于男性(P<0.05)。4)高血压组体质量、体质量指数(BMI)、腰臀比(WHR)、SBF、DBP、FPG、TG及LDL-C均高于正常对照组,HDL-C稍低于对照组(P<0.05)。5)高血压组超重肥胖、高TG、低HDL-C、MS及高血压家族史检出率高于正常对照组(P<0.05),两组间高FPG、糖尿病家族史检出率差异无统计学意义。6)Logistic多因素回归分析显示,女性高SBF危险性是男性的2.10倍(95%CI为1.47～2.98);年龄每增加1岁,DBP升高的危险性增加1.22倍(95%CI为1.08～1.38);有高血压家族史青少年高SBP的危险性是无家族史的1.64倍(95%CI为1.17～2.30);BMI每增加1 kg/m~2,SBP升高的危险性增加1.24倍(95%CI为1.20～1.28),DBP升高的危险性增加1.19倍,(95%CI是1.15～1.23)(P<0.01)。结论青少年高血压与MS密切相关,家族史、超重肥胖是引发青少年高血压的主要危险因素,要重视青少年心血管疾病的一级预防。更多还原

【Abstract】 Objective To explore the risk factors of hypertension and metabolic syndrome(MS) in adolescents. Methods A cross-sectional study was conducted in 3953 adolescents ages 12—18 years with 1698 subjects classified as preadolescents(age 12—15 years),2255 as adolescence.Height,weight,waist circumference,hip circumference,blood pressure and fasting plasma glucose(FPG),total cholesterol(TC),triglyceride(TG) and high-density lipoprotein cholesterol(HDL-C) were determined.Results 1) The prevalence rates of hypertension was 6.2%.2) The blood pressure in adolescents with overweights and obesity was higher than that of the normal BMI subjects.3) Prevalence rate of abnormal DBP in the adolescents was higher than that in preadolescents(P<0.05),and females had higher SBP than the males.4) Compared with the normal BP subjects,adolescent hypertension patients had significantly higher levels of weight,BMI,waist circumference,SBP,DBP,FPG,TG and LDL-C and with lower of HDL-C(P<0.05),while FPG and family history of diabetes seems not relate with the occurrence of hypertension.5) Logistic regression showed gender(OR:2.10,95%CI 1.47—2.98),BMI(OR: 1.24,95%CI 1.20-1.28,P<0.01) and family history(OR:1.64,95%CI 1.17-2.30,P<0.01) were as risk factors for SBP,and age(OR:l.22,95%CI 1.08-1.38,P<0.01),BMI(OR:1.19,95%CI 1.15-1.23,P<0.01) were the risk factors for DBP.Conclusion Hypertension closely related with MS in adolescents.Family history,overweight,obesities were the main predisposed factors associated with adolescents hypertension.更多还原