【摘要】 目的调查山东省不同地区的环境硒和人体硒水平,分析环境硒暴露与机体反应之间的关系,为证实低硒暴露水平与老年人群认知能力降低之间关系提供依据。方法选择2个环境硒水平相对高低不同的地区(高密县、淄川市);采集饮水、食物、土壤样品以及65～80岁老人的指甲、静脉血,分析硒含量。分析环境硒与人体硒之间的相关性。结果高密县、淄川市的环境硒含量分别为:土壤硒0.0423,0.04512mg/kg;饮水硒均<0.01mg/L;粮食硒(白面)0.0257,0.0934mg/kg;青菜硒0.0026,0.0415mg/kg。人体硒含量分别为:指甲硒0.4050,0.6048μg/g;全血硒0.1174,0.1474μg/ml。全部环境的硒水平与人体硒水平有良好的相关性,2个调查点的结果差异有统计学意义(P<0.01)。结论淄川市的调查点为环境硒适宜地区,高密县的调查点则环境硒缺乏地区,高密县、淄川市的人体硒含量均在正常水平范围。更多还原

【Abstract】 Objective To investigate the seleium levels of environment and human body in Shandong and to analyze the relationship between environmental selenium exposure and body selenium in old people.Methods Two study sites with different environmental selenium levels were selected.Soil,drinking water,food,blood and toenail samples of 500 rural Chinese aged 65～80 were collected from each of the two sites.Selenium contet in these samples was analyzed.Correlation between the selenium levels of environment and those of human body were analyzed statistically.Results Environmental selenium levels of the two study sites were as follows:the selenielm levels of soil were 0.042 3±0.012 7 and 0.451 2±0.022 4 mg/kg;the drinking water samples,<0.001 mg/L;foodstuff(wheat),0.025 7±0.001 4 and 0.093 4±0.024 mg/kg;greengrocery,0.002 6±0.000 6 and 0.041 5±0.034 2 mg/kg.Selenium levels of human body were as follows:blood selenium 0.053±0.007,0.097±0.013(μg/ml);toenail selenuum 0.211±0.039 and 0.434±0.098(μg/g).Conclusion Zichuan is among normal environmental selenium level regions,Gaomi is one of low environmental selenium level regions.The body selenium levels of the elder subjects in Gaimi,Zichuan are normal.There is a correaltion between selenium leves of environment and human body.更多还原