【摘要】 目的调查甘肃省天祝县居民幽门螺杆菌(Hp)感染状况及其流行相关因素。方法采用血清幽门螺杆菌IgG抗体金标免疫斑点渗滤法和14C-UBT检测天祝县1 495名常住居民幽门螺杆菌感染状况。结果天祝县幽门螺杆菌感染率74.0%,藏族、汉族及不同性别比较,其感染率差异均无统计学意义(P>0.05);山区感染率显著高于城区(P<0.01);随着年龄增长,幽门螺杆菌感染率逐渐升高,到30岁左右达到最高值;干部感染率显著低于农民、工人和医护人员(P<0.05);幽门螺杆菌感染有家庭聚集现象;幽门螺杆菌感染与饮水源显著相关,饮用自来水者感染率显著低于饮用井水和池塘/沟渠/河水者(P<0.01)。幽门螺杆菌感染与年人均收入、碗筷刷洗情况、便后洗手、上消化道症状显著相关(P<0.05)。结论天祝县居民幽门螺杆菌感染率较高,其感染率与经济状况、生活卫生习惯、饮用水源和上消化道症状等影响因素显著相关。更多还原

【Abstract】 Objective To investigate Helicobacter pylori infection in the population of Tianzhu areas,Gansu province.Methods With 1495 subjects selected in Tianzhu area,serologic H.pylori-Ig-G examination and 14-C-UBT were carried out.Results The H.pylori infective rate was 74.0%.Neither nationalities of Han and Zang nor gender had significant difference in H.pylori infective rate(P>0.05).In the population of mountain area,the H.pylori infective rate was significantly higher than that of in the city area(P<0.01).H.pylori infectived rate increased along with the age,and reached the highest value in age group around 30 years.H.pylori infective rate in the population of cadre was significantly lower than that of in worker,peasant,doctor and nurse(P<0.05).H.pylori infection had a familial clustering trend.The residents drinking water from pond,canal and river had a significantly higher prevalence of H.pylori infection than those with tap water(P<0.01).H.pylori infection was correlated with the overall economic status,the custom of sanitation and symptom of upper digestive tract disorders(P<0.05).Conclusion H.pylori infective rate was high in Tianzhu area and significantly related with factors such as economic status,sanitation habit,drinking water sources and symptom of upper digestive tract disorders.更多还原