【摘要】 目的评价超声对甲状腺髓样癌术前诊断的价值。方法回顾分析18例甲状腺髓样癌(MTC)患者的23个恶性结节的灰阶超声表现,包括结节的形态、回声水平、边界、内部回声和钙化类型及颈部淋巴结受累情况;比较术前超声检查与手术所见及病理学结果,同时结合甲状腺核素显像及相关实验室检查结果进行分析。结果在23个甲状腺MTC结节中,56.5%为单发,69.6%形态不规则,65.2%边界清晰,78.3%周边无声晕,91.3%为很低回声或低回声,78.3%内部回声不均,91.3%为实性或以实性成分为主,78.3%内部有微小或粗大钙化。病理证实为转移的颈部淋巴结中,80%为很低回声,80%内部可见钙化。结论MTC的灰阶超声表现既具有恶性甲状腺结节的一般特点,又有不同于乳头状癌的特殊表现,超声对术前定性诊断可提供一定的帮助。更多还原

【Abstract】 Objective To investigate the role of ultrasonography in the diagnosis of medullary thyroid carcinoma (MTC).Methods Gray-scale ultrasound appearances in 23 MTC nodules including nodular contours,echo texture,margins,internal architecture,calcifications,and involved cervical lymph nodes were retrospectively reviewed.Surgical and pathological findings,and data from scintigraphy and laboratory examinations were also evaluated.Results In ultrasonography the nodules manifested as solitary in 56.5%,irregular-shaped in 69.6%,well-defined in 65.2%,absent with "halo sign" in 78.3%,hypoechoic in 91.3%,heterogeneous in 78.3%,solid or predominantly solid in 91.3%,with inside microcalcifications or coarse calcifications in 78.3%.80% of metastatic cervical lymph nodes confirmed by pathology were hypoechoic,and 80% showed intrinsic calcifications on ultrasound.Conclusions The sonographic appearances of MTC were similar to other thyroid malignancy and had its own characteristics.Gray-scale ultrasonography can contribute to the diagnosis of MTC.更多还原