【摘要】 目的探讨超声造影对转移性肝癌的诊断价值。方法使用造影剂SonoVue,对30例转移性肝癌结节行超声造影检查,其中男22例,女10例;平均年龄为(57.8±11.5)岁;均经病理组织学证实。观察造影增强特征,并与增强CT/增强MRI、病理学检查进行对照分析。结果超声造影对转移性肝癌诊断的敏感性、特异性、准确性、阳性预测价值和阴性预测价值分别为93.8%、100%、99.2%、100%、99.1%。增强CT/MR对转移性肝癌诊断的敏感性、特异性、准确性、阳性预测价值和阴性预测价值分别为75%、99%、95%、92.3%、96.3%。对超声造影和增强CT/MRI诊断结果进行Fishersχ2检验,得P=0.254,故两者对转移性肝癌诊断统计学上无差异。结论超声造影能提高超声对转移性肝癌的诊断水平,对转移性肝癌的诊断及鉴别诊断有重要的价值,在对转移性肝癌的诊断率上与增强CT/MRI相当。更多还原

【Abstract】 Objective To investigate the clinical merit of the diagnosis of metastatic hepatic cancinoma(MHC)using contrast-enhanced ultrasound sonography(CEUS).Methods The characteristic-enhancement in metastatic hepatic cancinoma was examined and observed using ultrasound contrast agent-SonoVue and were compared with contrast enhanced CT/MRI and pathology in all cases.Results For contrast-enhanced ultrasound sonography,the sensitivity,specificity,diagnostic accuracy,positive and negative predictive value were 93.8%,100%,99.2%,100% and 99.1%,vs 75%,99%,95%,92.3% and 96.3%,respectively in contrast CT/MR,The differences between the diagnostic accuracy of metastatic hepatic cancinomas were not statistically significant(Fisher’s χ2 test:P=0.254 for CEUS versus CT/MR).Conclusions CEUS might increase the diagnostic accuracy of MHC on ultrasound sonography;It is a crucial and valuable method in the diagnosis and differential diagnosis of metastatic hepatic cancinoma with the some effect as contrast enhanced CT/MRI.更多还原