【摘要】 目的:为了提高银杏叶水提液的澄清度和药品质量,优化生产工艺。方法:基于光学吸收和散射原理,以絮凝率和总黄酮损失率为衡量指标,判断不同影响因素对絮凝效果的影响,并与醇沉法进行比较。又通过絮凝前后水提液的颗粒粒度情况进行验证。结果:壳聚糖对银杏叶水提液絮凝的最佳工艺条件:絮凝剂浓度1.071 g/L,絮凝温度40℃,体系pH值4.9。结论:壳聚糖对银杏叶水提液有较强的絮凝和选择性絮凝作用,絮凝效果明显优于醇沉法。更多还原

【Abstract】 AIM:In order to improve the clarity and quality of Ginkgo leaf water-extraction solution,and optimize the production process. METHODS:The experiment was based on the optical absoiption and scattering rate,flocculation rate and loss in flavanones were used as two main parameters to estimate the effect of influencing factors on flocculation.It could be proved by analyzing the particle size in water-extraction solution before and after flocculation. RESULTS:The best flocculation technological parameters of water-extraction solution of Ginkgo leaf with chitosan were as follows:at flocculant concentration of 1.071 g/L,flocculation temperature of 40(°C),pH of 4.9. CONCLUSION:The flocculation of water-extraction solution of Ginkgo leaf with chitosan is effective and selective,it has the advantage over ethanol precipitation method.更多还原