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非小细胞肺癌骨转移的中西医治疗探讨
Evaluate Treatment of NSCLC with Bone Metastasis Combined with Chinese Traditional Medicine
【摘要】 目的:探讨非小细胞肺癌(NSCLC)骨转移的中西医治疗方法。方法:回顾性分析200例非小细胞肺癌的临床资料。结果:发生骨转移部位包括肋骨134例(67%)、胸椎118例(59%)、骨盆106例(53%)、腰椎98例(49%)、四肢骨74例(37%)、肩胛骨20例(10%)、胸骨18例(9%)、颅骨23例(11.5%)。128例接受过化疗,98例接受过放射治疗,136例接受过氯屈膦酸二钠治疗,10例接受过核素治疗。发生骨转移后1年生存率为30.6%,生存期为1~26个月,中位生存期为8个月。其中有18例(9%)患者发生病理性骨折,包括四肢长骨12例,椎骨6例。12例四肢骨折当中3例行外科手术内固定,其余9例和椎骨压缩性骨折6例在抗肿瘤治疗的同时运用中医正骨治疗。结论:非小细胞肺癌骨转移的治疗是结合手术、放化疗、双磷酸盐药物等的多学科综合治疗;中医正骨是并发病理性骨折不能耐受手术患者的合适选择。
【Abstract】 OBJECTIVE: To evaluate treatment of NSCLC with bone metastasis combined with Chinese traditional medicine. METHODS: To analyse clinical information of 200 cases of NSCLC. RESULTS: 128 cases accepted chemotherapy, 98 cases accepted radiotherapy, 136 cases accepted clodronate clodronate diso dium drugs and 10 of them accepted nuclide therapy. 18 cases complicated with pathological fracture, 3 of them received surgery while other 15 received Chinese traditional bone-setting. CONCLUSION: Multidisciplinary synthetic therapy include surgery, chemo/radio-therapy, diphosphate drugs are necessary to control bone metastasis of NSCLC.Chinese traditional bone-setting is the proper choice for patient complicated with pathological fracture, especially when they can not tolerate surgery.
【Key words】 NSCLC; Bone metastasis; Chinese-western medicine; Bone-setting;
- 【文献出处】 中国医院用药评价与分析 ,Evaluation and Analysis of Drug-Use in Hospitals of China , 编辑部邮箱 ,2008年01期
- 【分类号】R734.2
- 【被引频次】2
- 【下载频次】197