【摘要】 目的:观察硝酸甘油控制性降压用于帕金森病立体定向手术的降压效果。方法:将60例帕金森病患者随机分为硝酸甘油组(降压组)30例、对照组30例。降压组采用0.02%硝酸甘油于手术前15min静滴控制性降压,对照组不给药,分别记录两组血压的基础值、切皮、颅骨钻孔、颅骨固定、射频治疗的血压值,并进行统计学对比。结果:在切头皮、颅骨钻孔、颅骨固定、射频治疗时段的血压值与对照组比较,有高度显著性差异(P<0.01)。结论:硝酸甘油控制性降压用于帕金森病立体定向手术,效果确切,且简单易行。更多还原

【Abstract】 Objective:To investigate the effects of deliberate hypertention inducted by nitroglycerin on blood pressure during stereotactic resection of brain.Methods:Sixty patients with Parkinsonism(31 males,29 females)aged 64～76 undergoing stereotactic resection of brain were randomly divided into tow groups: nitroglycerin group(n=30)and control group(n=30).In nitroglycerin group 0.02% nitroglycerin was given to reduce blood pressure with intravenous at 15 min before operation. In control group wasn’t given.SBP,DBP were monitored and compared at base value,skin incision,drilling skull,fixing skull and radiofrequence therpy between the two groups.Results:SBP,DBP were significantly higher in control group than that in nitroglycerin group at skin incision,drilling skull,fixing skull and radiofrequence therapy(P<0.01).Conclusion:The effect of deliberate hypotention inducted by nitroglycerin was more stable and performed easily.更多还原