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抗癌中药对肺癌标记物表达的影响及其疗效分析
Detecting the role Chinese herbs to the effect and machenism of lung cancer
【摘要】 目的:分析检测血液中癌胚抗原CEA mRNA、缓解率的变化,评价抗癌中药注射液对肺癌的疗效。方法:以肺癌(40例实验组、40例对照组)为对象,应用半巢式-聚合酶链反应技术检测患者注射抗癌中药前后血CEA mRNA水平、CR+PR+SD率。结果:治疗后,实验组CEA mRNA阳性结果为22.5%(9例),低于对照组的45%(18例)(P<0.05);CR+PR+SD率上升达80.0%(P<0.05)。结论:抗癌中药可有效治疗肺癌,CEA mRNA阳性例数减少,提高了临床有效率。
【Abstract】 Objective:To detect both the gene CEA mRNA and the remission rate of Chinese herbs in lung cancer. Methods: Both the experiment group and the control included 40 cases. CEA mRNA gene analysis was performed by semi-nested-polymerase chain reaction before and after treatment.The remission rate was observed. Results:The CEA mRNA positive rate 22.5%(9 cases) of the experimental group was lower than the control one’s 45%(18 cases)(P<0.05).The CR+PR+SD rate of the experimental group increased to 80.0%(P<0.05). Conclusion: Chinese herbs have some effects on lung cancer because the level CEA mRNA gene reduce after treatment. CR+PR rate and clinical benefit respones.
- 【文献出处】 中国医药导报 ,China Medical Herald , 编辑部邮箱 ,2008年02期
- 【分类号】R734.2
- 【被引频次】2
- 【下载频次】207