【摘要】 CYP2J2是一种广泛存在于人体心血管系统、肾脏及肝脏的P450酶。在人体不仅参与外源性物质的代谢,同时还参与花生四烯酸的代谢。由于其分布与功能的特点,在人体心血管系统具有重要调控作用。现就CYP2J2的基因及相应突变,分布以及其生理功能进行简单综述。更多还原

【Abstract】 As one of Human cytochromes P450,CYP2J2 is abundant in cardiovascular tissue and active in the metabolism of a variety of xenobiotics and arachidonic acid that make it to be one of the most important factor in cardiovascular system.This minireview will provide a general overview of CYP2J2 gene and its polymorphisms,distribution and physiological functions.更多还原