【摘要】 迄今,原发性肾病综合征发病机制尚未明确。近年来的研究表明,白细胞介素可能在其中起重要的作用,白细胞介素-1、-2、-6、-8、-12、-15和-18是其中的炎性因子,而白细胞介素-4、-10和-13是其中的抗炎性因子。白细胞介素在原发性肾病综合征中起着双向的作用,其之间存在复杂的相互调节关系,既相互诱导,又相互抑制。这些因素可能导致白细胞介素在原发性肾病综合征中作用的研究结果存在较大的差异。更多还原

【Abstract】 The pathogenesis of primary nephrotic syndrome(PNS) is not clear yet presently.The researches in recent years indicated that interleukin(IL) possibly played an important role in PNS.IL-1,IL-2,IL-6,IL-8,IL-12,IL-15 and IL-18 are inflammation factors in PNS,while IL-4,IL-10 and IL-13 are anti-inflammation factors in PNS.They play bidirectional role in PNS and have complex relationships among themselves.They can induce each other and inhibit each other as well.This might lead to the comparative differences amongy the results of the researches about interleukin’s effect in children PNS.更多还原