【摘要】 P2X受体是细胞外配体门控的阳离子通道,目前普遍认为可分为7个亚型,即P2X1~P2X7,当任何一种亚型的P2X受体与胞外三磷酸腺苷结合时,P2X通道打开,允许阳离子通过,如钠、钾、钙离子等(但以钙离子的通透性为著),继而引起一系列生理或病理现象。P2X受体在体内分布广泛,涉及到呼吸、消化、心血管、泌尿生殖以及骨骼肌肉系统和神经系统。更多还原

【Abstract】 P2X receptors are ligand-gated cation channels out of cells.Presently,It is considered to have 7 subunits,that is P2X1 to P2X7,Once any of these subtypes is combined ed with ATP,P2X can be opened,and allow the cations (such as,Na+、K+、Ca2+,and the permeability of Ca2+ is most conspicuous) to pass,which then will result in a series of physiological or pathological phenomena.P2X receptors have wide distribution in the body,including respiratory apparatus,digestive apparatus,cardiovascular system,genitourinary system,skeletal musculature and nervous system.更多还原