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HBeAg阳性慢性乙型肝炎抗病毒治疗药物的比较
Comparative Study on Anti-HBV Drugs in HBeAg Positive Chronic Hepatitis B
【摘要】 抗病毒治疗是慢性乙型肝炎治疗的关键。目前抗乙型肝炎病毒(HBV)药物主要有两大类,本文从抗病毒治疗的适应症、禁忌症、治疗效果、耐药性、依从性和治疗费用等方面对现有抗HBV药物进行了比较和分析,认为在选择抗HBV药物时,应遵循规范化与个体化相结合的原则,在患者能承受的费用范围内,尽量选择抗病毒作用强、耐药率低、耐受性良好的药物。
【Abstract】 Antiviral treatment is the key therapy of chronic hepatitis B.Currently there are two major types of approved anti-HBV drugs,and they are compared in the aspects of indications and contraindications of anti-HBV therapy,therapeutic efficacy,drug resistance,compliance and expenditure in this paper.When we choose anti-HBV drugs,the principle of the combination of normalization and individualization should follow,and we should select the drug with strong antivirus effect,low resistance rate,and good tolerance.
【关键词】 慢性乙型肝炎;
抗病毒治疗;
干扰素类;
核苷(酸)类似物;
【Key words】 chronic hepatitis B; antiviral treatment; interferon; nucleoside analogues;
【Key words】 chronic hepatitis B; antiviral treatment; interferon; nucleoside analogues;
- 【文献出处】 医学与哲学(临床决策论坛版) ,Medicine & Philosophy(Clinical Decision Making Forum Edition) , 编辑部邮箱 ,2008年11期
- 【分类号】R512.62
- 【被引频次】1
- 【下载频次】116